McNeill was hired by the NBC Blue Network to hosted an non-sponsored early morning variety show titled The Pepper Pot. McNeill thought name of the show was not in accordance with the show time which is started at 8:00 am. Later, He changed the show name as The Breakfast Club. The show was divided it into four segments, that called as ""the four calls to breakfast."" by McNeil.
Not long after His debut on radio, McNeill was addressed to improve the series became television series. He was known as Don McNeill's TV Club . The Breakfast Club was simulcast on television in 1954-1955. McNeill also appeared occasionally on game shows and the like, and in 1963, he hosted the short-lived game show Take Two, built around photo comparisons.
McNeill's radio series continued through this time, finally ending in 1968, at which point McNeill retired from entertainment, and from public life.